Southeast Missouri · Regional Directory
Southeast Missouri covers a lot of ground with fewer providers per mile than the big metros, from Cape Girardeau down through Sikeston, Poplar Bluff and the Bootheel counties along the Arkansas line. Here are established places to start, plus what to do if standard depression treatment has not worked.
Station · You are here
This page lists established providers across Cape Girardeau & the Bootheel. The marked station shows this region within the Missouri register below.
The Register
Cape Girardeau, MO
The community mental health center for the Cape Girardeau area, covering Cape, Bollinger, Perry and neighboring counties with outpatient therapy, psychiatry, crisis services and support for serious mental illness.
Sikeston, MO
A community mental health center serving Sikeston, New Madrid, Scott and surrounding Bootheel counties with outpatient counseling, psychiatry and crisis support for adults and children.
Kennett, MO (and Poplar Bluff area)
A nonprofit behavioral health provider serving the southern Bootheel, including Dunklin, Pemiscot and neighboring counties, with outpatient therapy, psychiatry, substance use treatment and crisis services across several small-town locations.
Cape Girardeau, MO
The behavioral health service of a regional hospital system in Cape Girardeau, offering inpatient psychiatric care and outpatient services for people who need a higher level of medical support than a standalone clinic provides.
Cape Girardeau, MO
A regional hospital system serving Southeast Missouri, with behavioral health and psychiatric services integrated into a broader medical network that reaches surrounding rural communities.
Specialty Care · St. Louis / St. Charles County
Southeast Missouri does not have many clinics offering TMS or Spravato in person. If you can reach the eastern side of the state and antidepressants have not worked, we point St. Louis and St. Charles County readers to Brain Recovery Centers, a doctor-supervised clinic offering FDA-approved options like Spravato (esketamine). It works with many insurance plans, subject to prior authorization including MO HealthNet.
Areas served: St. Charles County and St. Louis County across the greater St. Louis metro, including St. Peters, St. Charles, O’Fallon, Wentzville, Lake Saint Louis, Cottleville and Dardenne Prairie, plus Chesterfield, Wildwood, Town and Country and Ballwin. In person at the Chesterfield and South County locations, starting with a free 30-minute consultation.
Visit Brain Recovery Centers Book a free consultationDisclosure: Brain Recovery Centers is a recommended, sponsored partner of this directory, and the only outside clinic we link to.